Inhibition of Neuroblastoma cancer cells viability by ferromagnetic Mn doped CeO2 monodisperse nanoparticles mediated through reactive oxygen species
作者： Fazal Abbas , Tariq Jan , Javed Iqbal , M Sajjad Haider Naqvi , Ishaq Ahmad
DOI: 10.1016/J.MATCHEMPHYS.2016.01.042
关键词: Scanning electron microscope 、 Ferromagnetism 、 Raman spectroscopy 、 Dopant 、 Nanoparticle 、 Oxygen 、 Band gap 、 Analytical chemistry 、 Nanostructure 、 Photochemistry 、 Materials science
摘要: Abstract Here we report the Mn doping induced effects on structural, Raman, optical, magnetic and anticancer properties of CeO2 nanoparticles prepared via soft chemical route. Structural microstructural results infer that synthesized have single phase cubic fluorite structure in enhancement structural defects. Scanning electron microscopy reveal formation monodisperse having average particle size ranging from 30 to 41 nm. The optical absorbance spectroscopy analysis discloses band gap energy tailoring doping. Room temperature ferromagnetism (RTFM) has been found both as-prepared doped nanoparticles. This RTFM attributed ions surface defects such as oxygen vacancies. Finally, influence dopant cell viability reactive species (ROS) generation levels presence healthy cancerous cells studied. It observed differential cytotoxicity is strongly correlated with level ROS generation.
sci-hub.se 参考文章(43)
Fazal Abbas, J Iqbal, T Jan, M Sajjad H Naqvi, Asma Gul, Rashda Abbasi, Arshad Mahmood, Ishaq Ahmad, M Ismail, None, Differential cytotoxicity of ferromagnetic Co doped CeO2 nanoparticles against human neuroblastoma cancer cells Journal of Alloys and Compounds. ,vol. 648, pp. 1060- 1066 ,(2015) , 10.1016/J.JALLCOM.2015.06.195
Fazal Abbas, Tariq Jan, Javed Iqbal, M Sajjad H Naqvi, None, Fe doping induced enhancement in room temperature ferromagnetism and selective cytotoxicity of CeO2 nanoparticles Current Applied Physics. ,vol. 15, pp. 1428- 1434 ,(2015) , 10.1016/J.CAP.2015.08.007
José A. Rodriguez, Xianqin Wang, Jonathan C. Hanson, Gang Liu, Ana Iglesias-Juez, Marcos Fernández-Garcı́a, The behavior of mixed-metal oxides: Structural and electronic properties of Ce1-xCaxO2 and Ce1-xCaxO2-x Journal of Chemical Physics. ,vol. 119, pp. 5659- 5669 ,(2003) , 10.1063/1.1601595
Samuel W. Bennett, Arturo A. Keller, Comparative photoactivity of CeO2, γ-Fe2O3, TiO2 and ZnO in various aqueous systems Applied Catalysis B-environmental. ,vol. 102, pp. 600- 607 ,(2011) , 10.1016/J.APCATB.2010.12.045
ALESSANDRO TROVARELLI, Catalytic Properties of Ceria and CeO2-Containing Materials Catalysis Reviews-science and Engineering. ,vol. 38, pp. 439- 520 ,(1996) , 10.1080/01614949608006464
VD Araujo, W Avansi, a HB de Carvalho, ML Moreira, Elson Longo, C Ribeiro, Maria Inês Basso Bernardi, None, CeO2nanoparticles synthesized by a microwave-assisted hydrothermal method: evolution from nanospheres to nanorods CrystEngComm. ,vol. 14, pp. 1150- 1154 ,(2012) , 10.1039/C1CE06188G
Atul Asati, Santimukul Santra, Charalambos Kaittanis, J Manuel Perez, Surface-charge-dependent cell localization and cytotoxicity of cerium oxide nanoparticles. ACS Nano. ,vol. 4, pp. 5321- 5331 ,(2010) , 10.1021/NN100816S
Xin Liang, Xun Wang, Yuan Zhuang, Biao Xu, Simin Kuang, Yadong Li, Formation of CeO2−ZrO2Solid Solution Nanocages with Controllable Structures via Kirkendall Effect Journal of the American Chemical Society. ,vol. 130, pp. 2736- 2737 ,(2008) , 10.1021/JA7109629
K. Srinivas, M. Vithal, B. Sreedhar, M. Manivel Raja, P. Venugopal Reddy, Structural, Optical, and Magnetic Properties of Nanocrystalline Co Doped SnO2 Based Diluted Magnetic Semiconductors Journal of Physical Chemistry C. ,vol. 113, pp. 3543- 3552 ,(2009) , 10.1021/JP809146X
Leini Wang, Fanming Meng, Oxygen vacancy and Ce3+ ion dependent magnetism of monocrystal CeO2 nanopoles synthesized by a facile hydrothermal method Materials Research Bulletin. ,vol. 48, pp. 3492- 3498 ,(2013) , 10.1016/J.MATERRESBULL.2013.05.036