Coronary flow reserve: noninvasive measurement in humans with breath-hold velocity-encoded cine MR imaging.
作者： H Sakuma , L M Blake , T M Amidon , M O'Sullivan , D H Szolar
DOI: 10.1148/RADIOLOGY.198.3.8628864
关键词: Nuclear medicine 、 Coronary circulation 、 Coronary flow reserve 、 Diastole 、 Hemodynamics 、 Dipyridamole 、 Coronary vasodilator 、 Electrocardiography 、 Magnetic resonance imaging 、 Medicine
摘要: PURPOSE: To measure coronary vasodilator reserve with breath-hold velocity-encoded cine magnetic resonance (MR) imaging. MATERIALS AND METHODS: Eight healthy adult volunteers underwent 1.5-T MR Velocity-encoded images were acquired at seven to 13 temporal phases in 25 seconds, k-space segmentation and view-sharing reconstruction (+/- 1 m/sec velocity-encoding value) (repetition time msec/echo msec = 16/9). Flow velocity the left anterior descending (LAD) artery was measured twice before after administration of dipyridamole (0.56 mg per kilogram body weight). RESULTS: Peak diastolic flow LAD 14.8 cm/sec +/- 1.9 (mean standard deviation) baseline state. It increased significantly (P< .01) 46.3 10.2 administration, an average 3.14 0.59. Interstudy interobserver reproducibilities for measurement peak were, respectively, 9.5% 1.6 ...
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