Determination of methotrexate in human serum by high-performance liquid chromatography combined with pseudo template molecularly imprinted polymer

作者: Xiangjun Liu , Jizhong Liu , Yanyan Huang , Rui Zhao , Guoquan Liu

DOI: 10.1016/J.CHROMA.2009.06.018

关键词: Molecularly imprinted polymerMolecular imprintingChemistryBlood serumMethacrylic acidReversed-phase chromatographyEthylene glycol dimethacrylateHigh-performance liquid chromatographySolid phase extractionChromatographyOrganic chemistryAnalytical chemistryBiochemistryGeneral Medicine

摘要: A pseudo template molecularly imprinted polymer (MIP) was prepared for methotrexate (MTX) and a RP-HPLC method combined with the MIP was developed for the determination of …

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