Emerging Technologies to Create Inducible and Genetically Defined Porcine Cancer Models

作者: Lawrence B. Schook , Laurie Rund , Karine R. Begnini , Mariana H. Remião , Fabiana K. Seixas

DOI: 10.3389/FGENE.2016.00028

关键词: Genome editingEmerging technologiesCRISPRBioinformaticsDomestic animalComputational biologyBiologyOrganismCas9GenomeCancer

摘要: There is an emerging need for new animal models that address unmet translational cancer research requirements. Transgenic porcine models provide an exceptional opportunity due …

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