Efficacy of the type 2 diabetes prevention using lifestyle education program RCT

摘要: Introduction Self-administered lifestyle interventions have been suggested as an alternative to face-to-face delivery modes, although their efficacy remains uncertain. The aim of this study was evaluate the Type 2 diabetes mellitus Prevention Using LifeStyle Education (PULSE) Program, a self-administered and gender-tailored intervention for men at high risk developing mellitus. Design/setting A 6-month, assessor-blinded, parallel-group RCT conducted University Newcastle, Australia in 2012−2013. Participants Men (aged 18−65 years, BMI 25−40 kg/m , mellitus) were stratified by age ( 50 years) category (25.0−29.9, 30.0−35.9, 35.0−40 ) individually randomized (1:1 ratio) n =53) or waitlist control groups =48). Intervention group received PULSE which contained print video resources on weight loss (Self-Help, Exercise Diet using Internet Technology [SHED-IT] Weight Loss Program), diet modification, exercise prevention. no information until 6 months. Main outcome measures Data collected from September 2012 2013 analyzed 2014−2015. Linear mixed models (intention-to-treat) used determine X time interactions (differences between changes over time) months primary (weight), glycated hemoglobin, several secondary outcomes (significance level, p Results Differences mean baseline (group × interaction) favored (−5.50 kg, 95% CI=−7.40 −3.61 d =1.15), hemoglobin (−0.2%, CI=−0.3%, −0.1%, =0.002, =0.64), BMI, waist circumference, body fat percentage, aerobic fitness, lower muscular fitness (all Conclusions Program improved factors men, including hemoglobin. These findings provide evidence intervention, has potential dissemination community settings.