A radical cyclisation reaction based strategy to 2,3,5-tri- and tetrasubstituted furans
作者： A. Srikrishna , G. Sundarababu
DOI: 10.1016/S0040-4020(01)90088-2
关键词: Propargyl 、 Acetal 、 Chemistry 、 Free-radical reaction 、 Organic chemistry
摘要: Abstract Synthesis of 2,3,5-trisubstituted furans ( 5 ), starting from 2-methoxypropene and 1,3-disubstituted propargyl alcohols 3 , via the radical cyclisation bromo acetal 4 followed by aromatisation, is reported. Analogously, l-methoxycyclohexene furnished tetrasubstituted 6 .
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