作者: Wei-wu Pang , Shyuan Huang , Chien-Chiung Tung , Min-Ho Huang
DOI: 10.1097/00000539-200011000-00033
关键词: Patient-controlled analgesia 、 Analgesic 、 Prospective cohort study 、 Tramadol 、 Medicine 、 Anesthesia 、 Visual analogue scale 、 Adverse effect 、 Chemotherapy 、 Aspirin
摘要: UNLABELLED By using a patient-controlled analgesia (PCA) delivery system, we compared the clinical advantages and disadvantages of PCA with tramadol mixture plus lysine acetyl salicylate (a soluble aspirin). Fifty adult patients who had undergone major orthopedic surgeries were enrolled into prospective, randomized, double-blinded study. The general anesthesia was performed in standard manner. At beginning wound closure, an equal volume dose either 2.5 mg/kg (Group 1) or 1.25 + 12.5 2) administered slowly IV. These solutions continued postoperatively for IV PCA. Pain control, patient satisfaction, vital signs, adverse effects assessed 48 h. Visual Analog Scale =3 could be achieved group. Total consumption significantly less Group 2 than 1 (614 +/- 259 mg vs 923 354 mg) (P: < 0.05). Patients more alert Blood loss from surgical drain similar, 865 275 mL 702 345 2). We conclude that aspirin can used as effective safe adjuvant to after surgery. IMPLICATIONS Injectable patients. requirement is therefore reduced. This combination supports concept drugs other opioids