Patient-controlled analgesia with tramadol versus tramadol plus lysine acetyl salicylate.

作者: Wei-wu Pang , Shyuan Huang , Chien-Chiung Tung , Min-Ho Huang

DOI: 10.1097/00000539-200011000-00033

关键词: Patient-controlled analgesiaAnalgesicProspective cohort studyTramadolMedicineAnesthesiaVisual analogue scaleAdverse effectChemotherapyAspirin

摘要: UNLABELLED By using a patient-controlled analgesia (PCA) delivery system, we compared the clinical advantages and disadvantages of PCA with tramadol mixture plus lysine acetyl salicylate (a soluble aspirin). Fifty adult patients who had undergone major orthopedic surgeries were enrolled into prospective, randomized, double-blinded study. The general anesthesia was performed in standard manner. At beginning wound closure, an equal volume dose either 2.5 mg/kg (Group 1) or 1.25 + 12.5 2) administered slowly IV. These solutions continued postoperatively for IV PCA. Pain control, patient satisfaction, vital signs, adverse effects assessed 48 h. Visual Analog Scale

参考文章(10)
U. M Stamer, C Maier, S Grond, B Veh-Schmidt, E Klaschik, K. A Lehmann, Tramadol in the management of post-operative pain: a double-blind, placebo- and active drug-controlled study European Journal of Anaesthesiology. ,vol. 14, pp. 646- 654 ,(1997) , 10.1046/J.1365-2346.1994.00214.X
Wei-wu Pang, Martin S. Mok, Ming-Chou Ku, Min-Ho Huang, Patient-controlled analgesia with morphine plus lysine acetyl salicylate. Anesthesia & Analgesia. ,vol. 89, pp. 995- 998 ,(1999) , 10.1097/00000539-199910000-00032
W.J. KWEEKEL-DEVRIES, JOH. SPIERDIJK, H MATTIE, J.M.H. HERMANS, A NEW SOLUBLE ACETYLSALICYLIC ACID DERIVATIVE IN THE TREATMENT OF POSTOPERATIVE PAIN BJA: British Journal of Anaesthesia. ,vol. 46, pp. 133- 135 ,(1974) , 10.1093/BJA/46.2.133
Wei-Wu Pang, Martin S. Mok, Ching-Hsiung Lin, Teng-Fan Yang, Min-Ho Huang, Comparison of patient-controlled analgesia (PCA) with tramadol or morphine. Canadian Journal of Anaesthesia-journal Canadien D Anesthesie. ,vol. 46, pp. 1030- 1035 ,(1999) , 10.1007/BF03013197
R.M. JONES, J.N. CASHMAN, M.G. FOSTER, J.R. WEDLEY, A.P. ADAMS, COMPARISON OF INFUSIONS OF MORPHINE AND LYSINE ACETYL SALICYLATE FOR THE RELIEF OF PAIN FOLLOWING THORACIC SURGERY BJA: British Journal of Anaesthesia. ,vol. 57, pp. 259- 263 ,(1985) , 10.1093/BJA/57.3.259
M. D. VICKERS, D. PARAVICINI, S. MORANT, Comparison of tramadol with morphine for post-operative pain following abdominal surgery. European Journal of Anaesthesiology. ,vol. 12, pp. 265- 271 ,(1996) , 10.1097/00003643-199607000-00023
G LAURETTI, A MATTOS, I LIMA, Tramadol and beta-cyclodextrin piroxicam†‡Effective multimodal balanced analgesia for the intra-and postoperative period Regional Anesthesia and Pain Medicine. ,vol. 22, pp. 243- 248 ,(1997) , 10.1016/S1098-7339(06)80009-X
Pascale Picard, Jean E Bazin, Nathalie Conio, Franck Ruiz, Pierre Schoeffler, Ketorolac potentiates morphine in postoperative patient-controlled analgesia Pain. ,vol. 73, pp. 401- 406 ,(1997) , 10.1016/S0304-3959(97)00128-0
Jhi-Joung Wang, Yuan-Ji Day, Shung-Tai Ho, Wen-Jinn Liaw, Intravenous Tenoxicam Reduces Dose and Side Effects of PCA Morphine in Patients after Thoracic Endoscopic Sympathectomy Acta Anaesthesiologica Sinica. ,vol. 33, pp. 73- 77 ,(1995)
Pa. Insel, Analgesic-Antipyretic and Antiinflammatory Agents and Drugs Employed in the Treatment of Gout The Pharmacological Basic of Therapeutics. pp. 617- 657 ,(1996)