IgM antibody response to antigens prepared from vegetative and coccoid forms of Helicobacter pylori

作者: Manoucher Shahamat , Navid Alem , Mandana Asalkhou , Nina Hamedi , Neda Alem

DOI: 10.1016/J.YEXMP.2006.04.003

关键词: BiologyAntigenImmune systemMicrobiologySerologyHumoral immunityVirologyCagAHelicobacter pyloriAntibodySpirillaceaePathology and Forensic MedicineClinical biochemistryMolecular biology

摘要: This report describes the utility of antigens prepared from different coccoid and spiral forms Helicobacter pylori in a serological method. The presence IgM antibody to H. was determined 22 human sera on 24 strains pylori. Antigens form certain detected all confirmed positive sera. obtained cells same could not completely detect Testing boosted showed reduction number false negative, indicating that do have one or more antigenic fractions essential for accurate detection antibody. Our data suggest may lose CagA during conversion process regain it form. In conclusion, we antigen used antibodies methods should contain broad spectrum be culturable

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