Microvascular Endothelial Cells from Brain
作者： P. D. Bowman , M. du Bois , K. Dorovini-Zis , R. R. Shivers
DOI: 10.1007/978-3-642-75262-9_10
关键词: Nervous tissue 、 Distribution (pharmacology) 、 Transcytosis 、 Chemistry 、 Endothelial stem cell 、 Membrane 、 Vascular tone 、 Biophysics 、 Tight junction
摘要: In addition to providing a nonthrombogenic surface, synthesizing factor VIII, and participating in vascular tone regulation, most endothelial cells of the vasculature brain participate blood-brain barrier. The bloodbrain barrier severely restricts entry macromolecules into nervous tissue provides selective permeability variety other solutes [5, 23]. site this is which exhibit continuous tight junctions, very low amounts transcytosis, polar distribution transport carriers between luminal antiluminal plasma membranes.
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