Microstructured Surfaces Cause Severe but Non‐Detrimental Deformation of the Cell Nucleus
作者： Patricia M. Davidson , Hayriye Özçelik , Vasif Hasirci , Günter Reiter , Karine Anselme
关键词: Materials science 、 Cell nucleus 、 Composite material 、 Surface (mathematics) 、 Length scale 、 Deformation (meteorology)
摘要: Surface features on the length scale of organelles allow their manipulation. Here, we present observations an unexpected deformation nuclei within cells growing surfaces with micrometer‐sized pillars. Our results demonstrate that a microstructured surface can induce strong shape deformations in cells, without harmful consequences, and strongly suggest these are limited to cancerous cells.
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