作者: Enrique Hernandez de Anda , Suk-Hawn Lee , Charles O. Finne , David A. Rothenberger , Robert D. Madoff
DOI: 10.1007/S10350-004-0514-2
关键词: Survival analysis 、 Colorectal cancer 、 Ultrasound 、 Colorectal surgery 、 Surgery 、 Radical surgery 、 Abdominoperineal resection 、 Asymptomatic 、 Prospective cohort study 、 Medicine
摘要: This study was designed to investigate the role of a scheduled follow-up protocol using endorectal ultrasonography for diagnosis local recurrence after excision and radical surgery rectal cancer. A selected group 275 patients with invasive cancer followed prospectively by curative-intent (n = 108) or 167) reviewed. For radical-surgery group, results were compared 176 who had similar operations during same period time not entered in protocol. Excluded cancers removed snare excision, male treated abdominoperineal resection, endocavitary radiation. Student’s unpaired t-test used compare tumor patient characteristics. Survival curves estimated Kaplan-Meier method log-rank test. In local-excision 32 developed recurrence, 26 (81 percent) asymptomatic, 10 them (31 diagnosed only ultrasound. We found no difference rates salvage survival between ultrasound other methods. 12 5 (42 4 (33 More isolated underwent (4/9 patients; 44 without (3/13 23 percent), but differences significant. Endorectal identifies one-third asymptomatic recurrences that missed digital examination proctoscopic examination. However, impact earlier can be determined larger, prospective, randomized trial.