Inverse relationship of protein concentration and aggregation.

作者: Michael J. Treuheit , Andrew A. Kosky , David N. Brems

DOI: 10.1023/A:1015108115452

关键词: BiophysicsPhysical structureIncubationPharmacology toxicologyChemistryProtein concentrationAgrégationStereochemistryInversePharmaceutical technologyPolysorbate

摘要: Purpose. To determine the effect of protein concentration on aggregation induced through quiescent shelf-life incubation or shipping-related agitation.

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