Hemodynamic effects of dobutamine in children

作者: David J. Driscoll , Paul C. Gillette , Desmond F. Duff , Michael R. Nihill , Howard P. Gutgesell

DOI: 10.1016/0002-9149(79)90016-X

关键词: Internal medicineCardiac indexCardiologyDobutamineMedicineHeart rateStroke volumeCardiac catheterizationHeart diseaseAnesthesiaVascular resistanceCardiac output

摘要: Abstract Dobutamine is useful for augmenting cardiovascular function in adults. However, no information available on the action of dobutamine children. To determine its hemodynamic effects children, we infused into 12 children with congenital heart disease during diagnostic cardiac catheterization. We administered two doses: first 2 and then 7.75 μg/kg per min 10 minutes each. measured rate, output, systemic pulmonary arterial, right atrial capillary blood pressures before infusion dobutamine. Systemic vascular resistances, index stroke were calculated. Cardiac index, volume, arterial phasic mean increased significantly ( P Heart pressure resistance unchanged either dose noted adverse effect from drug.

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