Molecular Markers in Epithelial Ovarian Cancer

作者: Pat J. Morin

DOI: 10.1007/978-1-59745-346-2_3

关键词: Ovarian cancerClin oncolOvarian carcinomaMedicineOncologyInternal medicineDiseaseEpithelial ovarian cancerMortality rate

摘要: More than 50% of the women diagnosed with epithelial ovarian cancer will succumb to their disease. This high death rate is because two substantial clinical problems: 1. A typically late detection disease. 2. The common resistance tumors current therapeutic strategies.

参考文章(167)
A. Berchuck, B. J.M. Kerns, Robert C Bast, J. R. Marks, M. F. Kohler, P. A. Humphrey, Mutation and overexpression of p53 in early-stage epithelial ovarian cancer. Obstetrics & Gynecology. ,vol. 81, pp. 643- 650 ,(1993)
Jeffrey S. Ross, Fan Yang, Bhaskar V. S. Kallakury, Christine E. Sheehan, Robert A. Ambros, Patrick J. Muraca, HER-2/neu oncogene amplification by fluorescence in situ hybridization in epithelial tumors of the ovary. American Journal of Clinical Pathology. ,vol. 111, pp. 311- 316 ,(1999) , 10.1093/AJCP/111.3.311
Laframboise S, McLaughlin J, Chapman W, Andrulis Il, p53 mutations in epithelial ovarian cancers: possible role in predicting chemoresistance. Cancer Journal. ,vol. 6, pp. 302- ,(2000)
Robert E. Scully, Robert C. Bast, Robert C. Knapp, Nina Einhorn, Paul Hall, Vincent R. Zurawski, Kerstin Sjövall, Prospective evaluation of serum CA 125 levels for early detection of ovarian cancer. Obstetrics & Gynecology. ,vol. 80, pp. 14- 18 ,(1992)
R.C. Bast, F.-J. Xu, Y.-H. Yu, S. Barnhill, Z. Zhang, G.B. Mills, CA 125: the past and the future. International Journal of Biological Markers. ,vol. 13, pp. 179- 187 ,(1998) , 10.1177/172460089801300402
S Pilotti, M I Colnaghi, G Spatti, S C Righetti, F Zunino, S Ménard, G Della Torre, M A Pierotti, F Ottone, M Cornarotti, S Oriana, G L Bresciani, C Lavarino, S Böhm, A Comparative Study of p53 Gene Mutations, Protein Accumulation, and Response to Cisplatin-based Chemotherapy in Advanced Ovarian Carcinoma Cancer Research. ,vol. 56, pp. 689- 693 ,(1996)
Ann-Marie Martoglio, Brian D. M. Tom, Michael Starkey, Anthony N. Corps, D. Stephen Charnock-Jones, Stephen K. Smith, Changes in tumorigenesis- and angiogenesis-related gene transcript abundance profiles in ovarian cancer detected by tailored high density cDNA arrays. Molecular Medicine. ,vol. 6, pp. 750- 765 ,(2000) , 10.1007/BF03402191
William Cliby, Gary Keeney, Viji Shridhar, Julie Staub, Kimberly Kalli, Ajay Pandita, Rosemarie Schmandt, Gordon B. Mills, Robert Bast, Lynn C. Hartmann, Ami Sen, C. David James, John Lee, Patrick Roche, Steve Iturria, Karen Lu, Eric Calhoun, Mike Morrissey, Fergus J. Couch, Rajeswari Avula, Jim Lillie, David I. Smith, Genetic Analysis of Early- versus Late-Stage Ovarian Tumors Cancer Research. ,vol. 61, pp. 5895- 5904 ,(2001)
Marleen van Gramberen, Stefano Fracchioli, Andreas Scorilas, Marco Massobrio, Ulf-Hakan Stenman, Dionyssios Katsaros, Roberto Bellino, Liu-Ying Luo, Ignace Vergote, Alfthan Henrik, Eleftherios P Diamandis, Henk de Bruijn, Ate G J van der Zee, The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis Cancer Research. ,vol. 63, pp. 807- 811 ,(2003)
Viji Shridhar, Steve Kovats, Julie Staub, Ami Sen, John Lee, Jeremy Chien, Rajeswari Avula, Jim Lillie, David I. Smith, Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization Cancer Research. ,vol. 62, pp. 262- 270 ,(2002)