Can infants be protected by means of maternal vaccination

作者: S. Esposito , S. Bosis , L. Morlacchi , E. Baggi , C. Sabatini

DOI: 10.1111/J.1469-0691.2012.03936.X

关键词: PopulationTetanusDiseaseVaccinationPregnancyImmunologyAdverse effectImmunizationMedicineVaccination schedule

摘要: The administration of vaccines is not usually recommended in pregnant women because a fear severe adverse events for the fetus. However, contraindication to vaccination applies only based on live attenuated viruses theoretical possibility that they might infect In contrast, use several inactivated useful and recommended. As result transplacental passage antibodies, maternal immunization can reduce risk vaccine-preventable diseases may occur first months life before start or completion suggested schedule. One best examples against influenza protect from disease lead hospitalization death significantly higher number cases than general population induce protective specific antibody levels as well being effective infants life. Other are vaccinations tetanus, pertussis, pneumococcal infections Haemophilus influenzae type b infection. This review analyses advantages limitations revealed by experience main publications.

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