Primary pulmonary tumours of nerve sheath origin

作者: W.G. McCLUGGAGE , H. BHARUCHA

DOI: 10.1111/J.1365-2559.1995.TB01438.X

关键词: Respiratory diseaseLungHistological diagnosisPathologySchwannomaNerve sheathImmunohistochemistryBiopsyBiologyPeripheral Nerve Sheath

摘要: Primary intrapulmonary tumours of nerve sheath origin are extremely rare. We describe the clinicopathological features four such peripheral tumours, two benign and malignant. Of one was a typical schwannoma other an ancient or degenerated schwannoma. The endobronchial in origin, diagnosis being established by small bronchoscopic biopsy. histological malignant tumour required immunohistochemical and/or ultrastructural evidence differentiation. One arose patient with Von-Recklinghausen's disease. Both behaved aggressively development multiple metastases, despite markedly different appearance tumours. Flow cytometric analysis nuclear DNA content performed on all which showed diploid profile.

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