DNA ligase IV suppresses medulloblastoma formation.
作者： Peter J. McKinnon , Youngsoo Lee
DOI:
关键词: DNA damage 、 Synaptophysin 、 LIG4 、 Biology 、 Medulloblastoma 、 Carcinogenesis 、 Immunology 、 DNA repair 、 Apoptosis 、 Molecular biology 、 DNA ligase
摘要: Substantial neural defects are often present in mice with targeted inactivation of DNA repair factors such as DNA ligase IV (Lig4). Whereas Lig4 −/− mice undergo widespread neural …
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