Immunohistochemical differentiation and localization analysis of sweat glands in the adult human axilla.

摘要: BACKGROUND: The classic concept of axillary glands differentiates between eccrine glands, producing abundant clear, nonodorous sweat; and apocrine excreting small amounts turbid, odorous milky sweat. A third type sweat the "apoeccrine" were recently identified. To define different types their location number, authors carried out a prospective histologic study on adult human skin, including various immunohistochemical markers. METHODS: Forty-three consecutive Caucasian, subjectively normhidrotic patients, who underwent surgical procedure in axilla unrelated to included study. For verification normhidrosis, gravimetric test was by measuring amount secretion per minute. Then, 1 x 1-cm piece skin subcutaneous tissue excised apex axilla, divided into three samples--altogether, 129 samples--and processed for examination. RESULTS: In dermis, found only very few (average, 0.3 gland/cm 12 percent all patients) 0.1 4.7 patients), no apoeccrine any patient. tissue, mean number centimeter squared 10 nine six glands. CONCLUSIONS: authors' Caucasian subjects, or most near border dermis not dermis. extremely hyperfunctioning recommend less radical methods, with preservation based knowledge that are localized tissue.