Diagnosis and treatment of hypopituitarism: An update

摘要: Diagnosis and treatment of patients with hypopituitarism needs careful clinical evaluation individual optimization. Symptoms are variable, often insidious in onset dependent on the degree hormone deficiency. can be straightforward by measuring reduced basal levels. Frequently, dynamic stimulation tests indicated equivocal levels or to diagnose partial deficiencies. Knowledge use limitations these is mandatory for proper interpretation. Hormone replacement therapy should individualized, taking into account possible interactions. Persisting symptoms quality life frequently reported, explained by, at least part, intrinsic imperfections strategies mimicking normal secretion. In present overview, principles diagnosis discussed.