Frequency of hereditary colorectal carcinoma

作者: Jukka-Pekka Mecklin

DOI: 10.1016/0016-5085(87)90565-8

关键词: Risk factorGastroenterologySyndrome typeUlcerative colitisLynch Syndrome IIColorectal cancerCancer FamilyMedicineFamily historyCancerInternal medicine

摘要: Abstract The frequency of hereditary colorectal carcinoma was evaluated in a study group consisting all patients (n = 468) diagnosed one Finnish county (0.25 million inhabitants) during the period 1970–1979. cancer family syndrome type nonpolyposis emerged as most common verifiable risk factor for colon involving 3.8%–5.5% this study. frequencies familial adenomatosis and ulcerative colitis were 0.2% 0.6%, respectively. As diagnostic method based on history patients, only those families with inherited cases two or more generations could be identified. cannot basis single patient, so observed 4%–6% may still represent an underestimate. young, accounting 29%–39% under 50 yr age, their tumors located predominantly (65%) right hemicolon. high among indicates importance studying every new patient.

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