Baldness and testicular cancer: the EPSAM case-control study.
作者： G. Moirano , D. Zugna , C. Grasso , P. Lista , L. Ciuffreda
DOI: 10.1111/ANDR.12148
关键词: Etiology 、 Medicine 、 Reproductive medicine 、 Physiology 、 Androgen 、 Inverse Association 、 Case-control study 、 Male health 、 Hormone 、 Testicular cancer 、 Gynecology
摘要: The etiology of testicular cancer is largely unexplained. Research has mainly focused on prenatal exposures, especially to sex hormones, while less attention been paid exposures that may act also postnatally. As baldness previously associated with risk we and body hairiness, which are both androgen activity. We used data the Postnatal Exposures Male Health (EPSAM) study, a case-control study conducted in Province Turin, Italy, involving cases diagnosed between 1997 2008. Information was collected using mailed questionnaires. Analyses included 255 459 controls. calculated ORs 95% CIs estimate among those who developed hairiness. found an inverse association (OR: 0.67, CI: 0.46-0.98) hairiness 0.78, 0.53-1.16), although latter had wider CIs. consistent results from previous studies. These suggest androgens activity influence risk.
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