Pathogenesis of Keratinocyte Carcinomas and the Therapeutic Potential of Medicinal Plants and Phytochemicals.

作者: Danielle Twilley , Namrita Lall , Sreejarani Kesavan Pillai , Suprakas Sinha Ray , Andrea Jess Josiah

DOI: 10.3390/MOLECULES26071979

关键词: MedicineCarcinomaKeratinocyteAdverse effectSkin cancerCancer researchIn vivoEpidermis (botany)TransdermalBasal cell carcinoma

摘要: Keratinocyte carcinoma (KC) is a form of skin cancer that develops in keratinocytes, which are the predominant cells present epidermis layer skin. comprises two sub-types, namely basal cell (BCC) and squamous (SCC). This review provides holistic literature assessment origin, diagnosis methods, contributing factors, current topical treatments KC. Additionally, it explores increase KC cases occurred globally over past ten years. One principal concepts highlighted this article adverse effects linked to conventional treatment methods how novel strategies combine phytochemistry transdermal drug delivery systems offer an alternative approach for treatment. However, more vitro vivo studies required fully assess efficacy, mechanism action, safety profile these phytochemical based chemotherapeutics.

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