Egyptian herbal tea infusions' antioxidants and their antiproliferative and cytotoxic activities against cancer cells
作者： Hosam O. Elansary , Eman A. Mahmoud
DOI: 10.1080/14786419.2014.951354
关键词: Rosmarinus 、 Rosmarinic acid 、 Traditional medicine 、 Herbal tea 、 DPPH 、 Mentha longifolia 、 Caffeic acid 、 Mentha suaveolens 、 Origanum 、 Botany 、 Chemistry
摘要: The antioxidant, antiproliferative and cytotoxic activities against different human cancer cells were investigated in local recently introduced plants of Mentha sp., Rosmarinus officinalis L. (ROL) Origanum majorana (OML). ROL exhibited the highest antioxidant (IC50 8.4 ± 0.2 μg/mL) followed by OML mint species such as suaveolens 'apple mint' longifolia exhibiting moderate activities. HPLC analysis leaf extract revealed that rosmarinic acid is main component caffeic acid. Herbal extracts varied their proliferation inhibition cytotoxicity HeLa, MCF-7 Jurkat a dose-dependent matter. activity detected mint. Local herbs might have potential role anticancer natural medicines addition to high due presence phenolics aqueous tea extracts.
sci-hub.se 参考文章(16)
Constantine D. Stalikas, Phenolic acids and flavonoids: occurrence and analytical methods. Methods of Molecular Biology. ,vol. 610, pp. 65- 90 ,(2010) , 10.1007/978-1-60327-029-8_5
Verica Dragović-Uzelac, Tea Kulišić, Mladen Miloš, Antioksidativna aktivnost infuza mravinca, timijana i majčine dušice Food Technology and Biotechnology. ,vol. 44, pp. 485- 492 ,(2006)
K. V. Peter, Handbook of Herbs and Spices ,(2012)
Carl H. Beckman, Phenolic-storing cells : keys to programmed cell death and periderm formation in wilt disease resistance and in general defence responses in plants? Physiological and Molecular Plant Pathology. ,vol. 57, pp. 101- 110 ,(2000) , 10.1006/PMPP.2000.0287
Vassiliki G. Kontogianni, Goran Tomic, Ivana Nikolic, Alexandra A. Nerantzaki, Nisar Sayyad, Stanislava Stosic-Grujicic, Ivana Stojanovic, Ioannis P. Gerothanassis, Andreas G. Tzakos, Phytochemical profile of Rosmarinus officinalis and Salvia officinalis extracts and correlation to their antioxidant and anti-proliferative activity. Food Chemistry. ,vol. 136, pp. 120- 129 ,(2013) , 10.1016/J.FOODCHEM.2012.07.091
H. J. Damien Dorman, Müberra Koşar, Kirsti Kahlos, Yvonne Holm, Raimo Hiltunen, Antioxidant Properties and Composition of Aqueous Extracts from Mentha Species, Hybrids, Varieties, and Cultivars Journal of Agricultural and Food Chemistry. ,vol. 51, pp. 4563- 4569 ,(2003) , 10.1021/JF034108K
Deepika Jain, Neelam Pathak, Saba Khan, Gorantla Venkata Raghuram, Arpit Bhargava, Ravindra Samarth, Pradyumna Kumar Mishra, Evaluation of Cytotoxicity and Anticarcinogenic Potential of Mentha Leaf Extracts International Journal of Toxicology. ,vol. 30, pp. 225- 236 ,(2011) , 10.1177/1091581810390527
Ryszard Amarowicz, Zofia ZÌegarska, Ryszard RafaÅowski, Ronald B. Pegg, Magdalena KaramacÌ, Agnieszka KosinÌska, Antioxidant activity and free radical‐scavenging capacity of ethanolic extracts of thyme, oregano, and marjoram European Journal of Lipid Science and Technology. ,vol. 111, pp. 1111- 1117 ,(2009) , 10.1002/EJLT.200800170
María José del Baño, Juan Lorente, Julián Castillo, Obdulio Benavente-García, José Antonio del Río, Ana Ortuño, Karl-Werner Quirin, Dieter Gerard, Phenolic diterpenes, flavones, and rosmarinic acid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. Antioxidant activity. Journal of Agricultural and Food Chemistry. ,vol. 51, pp. 4247- 4253 ,(2003) , 10.1021/JF0300745
Manjeshwar Shrinath Baliga, Rosmy Jimmy, Karadka Ramdas Thilakchand, Venkatesh Sunitha, Neeta Raghavendra Bhat, Elroy Saldanha, Suresh Rao, Pratima Rao, Rajesh Arora, Princy L Palatty, None, Ocimum Sanctum L (Holy Basil or Tulsi) and Its Phytochemicals in the Prevention and Treatment of Cancer Nutrition and Cancer. ,vol. 65, pp. 26- 35 ,(2013) , 10.1080/01635581.2013.785010