A phosgene and peroxide-free one-pot tandem synthesis of isatoic anhydrides involving anthranilic acid, Boc anhydride, and 2-chloro-N-methyl pyridinium iodide
作者： Chhaya Verma , Somesh Sharma , Arunendra Pathak
DOI: 10.1016/J.TETLET.2013.10.034
关键词: Peroxide 、 Iodide 、 Pyridinium 、 Anthranilic acid 、 Carbamate 、 Tandem 、 Organic chemistry 、 Chemistry 、 Phosgene 、 Isatoic anhydride
摘要: Abstract A phosgene and peroxide-free approach for the synthesis of isatoic anhydrides has been described. The involves carbamate formation with Boc anhydride followed by in situ cyclization to afford anhydride. importance this synthetic strategy is ease operation, scalability, preparation from readily available raw materials.
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