The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction
作者： Mathias Müller , James Briscoe , Carl Laxton , Dmitry Guschin , Andrew Ziemiecki
DOI: 10.1038/366129A0
关键词: Alpha interferon 、 Interferon alfa 、 Interferon gamma 、 Cell biology 、 Biology 、 Biochemistry 、 Tyrosine kinase 、 TYK2 Kinase 、 Receptor tyrosine kinase 、 Tyrosine kinase 2 、 Signal transduction
摘要: … tyrosine kinase JAK1 and is completely defective in interferon response. Complementation of this mutant with JAK1 restored the response, establishing the requirement for JAK1 in both …
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