Demographic Impact of Epilepsy in Africa: Results of a 10-year Cohort Study in a Rural Area of Cameroon

作者: Joseph Kamgno , Sébastien D. S. Pion , Michel Boussinesq

DOI: 10.1046/J.1528-1157.2003.59302.X

关键词: EpilepsyEpidemiologyMedicineSurgeryDemographyRelative riskInjury preventionMarital statusPoison controlCause of deathCohort study

摘要: Summary: Purpose: To evaluate the demographic impact of epilepsy a rural area Africa. Methods: A cohort study was conducted between 1991 and 2001 in Mbam Valley (Cameroon) on two groups subjects (one persons with epilepsy, other control individuals matched for sex, age, village residence). At end follow-up, information mortality, marital status, numbers offspring obtained from 128 pairs subjects. Results: Thirty-seven (28.9%) six (4.7%) controls died 2001. The relative risk dying during follow-up among group people compared controls, 6.2 (95% CI, 2.7–14.1). most frequent causes death were status epilepticus, sudden unexpected (SUDEP), drowning. Of 90 pairs, which both members still alive 2001, 15 (16.7%) married as 53 (58.9%) controls. mean number children 0.9 1.7 (p < 0.0001). Conclusions: Health personnel should be trained sensitized about devastating effect this neglected disease developing countries. In those areas where onchocerciasis programs are organized by using community-directed-treatment approach, possibility that ivermectin distributors could also responsible distributing antiepileptic drugs considered.

参考文章(38)
N. Peshu, R. W. Snow, J. E. Rogers, R. E. M. Williams, V. O. Mung'ala, The prevalence of epilepsy among a rural Kenyan population. Its association with premature mortality. Tropical and geographical medicine. ,vol. 46, pp. 175- 179 ,(1994)
Gustavo C. Roman, N. Senanayake, Epidemiology of epilepsy in developing countries. Bulletin of The World Health Organization. ,vol. 71, pp. 247- 258 ,(1993)
Corry Gerrits, A West African epilepsy focus. The Lancet. ,vol. 321, pp. 358- 358 ,(1983) , 10.1016/S0140-6736(83)91663-X
Lena Nilsson, T. Tomson, B. Y. Farahmand, V. Diwan, P. G. Persson, Cause‐Specific Mortality in Epilepsy: A Cohort Study of More Than 9,000 Patients Once Hospitalized for Epilepsy Epilepsia. ,vol. 38, pp. 1062- 1068 ,(1997) , 10.1111/J.1528-1157.1997.TB01194.X
Linda V. Dansky, Eva Andermann, Frederick Andermann, Marriage and fertility in epileptic patients. Epilepsia. ,vol. 21, pp. 261- 271 ,(1980) , 10.1111/J.1528-1157.1980.TB04072.X
Mayris Poloner Webber, W. Allen Hauser, Ruth Ottman, John F. Annegesr, Fertility in persons with epilepsy: 1935-1974. Epilepsia. ,vol. 27, pp. 746- 752 ,(1986) , 10.1111/J.1528-1157.1986.TB03605.X
Paul Nchoji Nkwi, Flavius Tioko Ndonko, The epileptic among the Bamileke of Maham in the Nde Division, West Province of Cameroon. Culture, Medicine and Psychiatry. ,vol. 13, pp. 437- 448 ,(1989) , 10.1007/BF00052050
Redda Tekle-Haimanot, Mekonnen Abebe, Lars Forsgren, Ayele Gebre-Mariam, Jan Heijbel, Gösta Holmgren, Jan Ekstedt, Attitudes of rural people in central Ethiopia toward epilepsy Social Science & Medicine. ,vol. 32, pp. 203- 209 ,(1991) , 10.1016/0277-9536(91)90061-G