Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
作者： Diego L. Medina , Simone Di Paola , Ivana Peluso , Andrea Armani , Diego De Stefani
DOI: 10.1038/NCB3114
关键词: Lysosome 、 Cellular homeostasis 、 Biochemistry 、 Autophagy 、 TFEB 、 Calcium signaling 、 Calcineurin 、 Transcriptional regulation 、 Cell biology 、 Phosphatase 、 Biology
摘要: … GCaMP3 Ca 2+ imaging was performed in HEK cells that stably express GCaMP3–ML1, which are lysosome-targeted genetically encoded Ca 2+ sensors 36 . The fluorescence …
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Ruth Bargal, Nili Avidan, Edna Ben-Asher, Zvia Olender, Marcia Zeigler, Ayala Frumkin, Annick Raas-Rothschild, Gustavo Glusman, Doron Lancet, Gideon Bach, None, Identification of the gene causing mucolipidosis type IV Nature Genetics. ,vol. 26, pp. 118- 121 ,(2000) , 10.1038/79095
Simon Plyte, Marianna Boncristiano, Elena Fattori, Federico Galvagni, Silvia Rossi Paccani, M. Bernardetta Majolini, Salvatore Oliviero, Gennaro Ciliberto, John L. Telford, Cosima T. Baldari, Identification and Characterization of a Novel Nuclear Factor of Activated T-cells-1 Isoform Expressed in Mouse Brain Journal of Biological Chemistry. ,vol. 276, pp. 14350- 14358 ,(2001) , 10.1074/JBC.M007854200
Anthony J Morgan, Frances M Platt, Emyr Lloyd-Evans, Antony Galione, None, Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease Biochemical Journal. ,vol. 439, pp. 349- 374 ,(2011) , 10.1042/BJ20110949
Joerg Heineke, Oliver Ritter, Cardiomyocyte calcineurin signaling in subcellular domains: from the sarcolemma to the nucleus and beyond. Journal of Molecular and Cellular Cardiology. ,vol. 52, pp. 62- 73 ,(2012) , 10.1016/J.YJMCC.2011.10.018
Carmine Settembre, Alessandro Fraldi, Diego L. Medina, Andrea Ballabio, Signals from the lysosome: a control centre for cellular clearance and energy metabolism Nature Reviews Molecular Cell Biology. ,vol. 14, pp. 283- 296 ,(2013) , 10.1038/NRM3565
K. Pattni, M. Jepson, H. Stenmark, G. Banting, A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells Current Biology. ,vol. 11, pp. 1636- 1642 ,(2001) , 10.1016/S0960-9822(01)00486-9
C. Settembre, C. Di Malta, V. A. Polito, M. G. Arencibia, F. Vetrini, S. Erdin, S. U. Erdin, T. Huynh, D. Medina, P. Colella, M. Sardiello, D. C. Rubinsztein, A. Ballabio, TFEB links autophagy to lysosomal biogenesis. Science. ,vol. 332, pp. 1429- 1433 ,(2011) , 10.1126/SCIENCE.1204592
Zhifen Yang, Daniel J Klionsky, Mammalian autophagy: core molecular machinery and signaling regulation Current Opinion in Cell Biology. ,vol. 22, pp. 124- 131 ,(2010) , 10.1016/J.CEB.2009.11.014
Maria T. Bassi, Marta Manzoni, Eugenio Monti, Maria T. Pizzo, Andrea Ballabio, Giuseppe Borsani, Cloning of the Gene Encoding a Novel Integral Membrane Protein, Mucolipidin—and Identification of the Two Major Founder Mutations Causing Mucolipidosis Type IV The American Journal of Human Genetics. ,vol. 67, pp. 1110- 1120 ,(2000) , 10.1016/S0002-9297(07)62941-3
Anthony J. Morgan, Lianne C. Davis, Siegfried K.T.Y. Wagner, Alexander M. Lewis, John Parrington, Grant C. Churchill, Antony Galione, Bidirectional Ca2+ signaling occurs between the endoplasmic reticulum and acidic organelles Journal of Cell Biology. ,vol. 200, pp. 789- 805 ,(2013) , 10.1083/JCB.201204078