Nosocomial Infection and Fatality in Medical and Surgical Intensive Care Unit Patients

作者: Donald E. Craven

DOI: 10.1001/ARCHINTE.1988.00380050165024

关键词: MedicineStepwise regressionRelative riskUrinary systemSurgical intensive care unitResuscitationCase fatality rateEmergency medicineSurgeryIntensive care unitComa

摘要: • We prospectively studied 526 patients admitted to the medical intensive care unit (MICU) and 799 surgical (SICU) at a municipal hospital over 20-month period. Rates of nosocomial infection were higher in SICU (31% vs 24%). The had more urinary tract infections, bacteremias, wound MICU older, acute physiology scores on admission often with shock or coma. likely have received prior antibiotic therapy significantly numbers endotracheal tubes, arterial lines, central venous indwelling bladder catheters. Of 23 variables univariately associated infection, only five remained significant after entry into stepwise regression models. fatality rate than did (18% 10%), but relative risk death following was 3.5 for both groups. Thirty fatality; nine analysis by logistic regression. (Arch intern Med1988;148:1161-1168)

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