Evidence for time–place learning in the Morris water maze without food restriction but with increased response cost

摘要: Time-place learning is the ability to distinguish between resources that vary in location at different times of day. Only one previous report has demonstrated successful time-place without using food as reward. In this experiment, satiated rats failed form discriminations a Morris water maze while deprived did, leading conclusion system activation necessary for learning. However, addition activation, response cost was also increased, which previously been be effective allowing formation discriminations. The purpose these two experiments test whether or heightened allowed maze. first we replicate failure find restriction and increased cost. second found discrimination. implications result are discussed light timing mechanism used discriminations, nature cost, event-time-place tripartite association.