Detection of Myocardial Ischemia in Patients With Diabetes Mellitus

作者: Frans J. Th. Wackers , Barry L. Zaret

DOI: 10.1161/CIRC.105.1.5

关键词: Diabetes mellitusInternal medicineDiseaseMyocardial infarctionMedicineCoronary artery diseaseIschemiaCardiologyAsymptomaticRisk factorMyocardial perfusion imagingPhysiology (medical)Cardiology and Cardiovascular Medicine

摘要: The combination of clinical coronary artery disease and diabetes mellitus is a harbinger adverse outcome. Recently, in jointly issued statement, the American Diabetes Association, National Heart, Lung, Blood Institute, Juvenile Foundation International, Institute Digestive Kidney Diseases, Heart Association indicated importance as major risk factor for cardiovascular disease.1,2 Patients with often have premature disease; asymptomatic an advanced stage when detected.3 In general, outcome patients poorer than those without diabetes, diabetic patient may be less amenable to favorable interventional treatment compared nondiabetic population.4–6 Moreover, it seems that women disease, overall has not improved extent observed men, despite aggressive medical or treatment.7 Such observations led need more approaches preventive, diagnostic, therapeutic strategies mellitus. See p 32 Stress radionuclide myocardial perfusion imaging (MPI) used widely evaluate suspected known disease. A large body evidence attests high diagnostic yield stress MPI its important incremental prognostic value over both angiographic variables prediction acute events.8,9 degree abnormalities on are related directly greater abnormality, likelihood future cardiac events. On other hand, unequivocally normal associated excellent event rate <1% per year. …

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