Gene expression of neurotrophic factors in human brain tumors.

作者: Terry Lichtor , Hirotaka Yamamoto , Mark E. Gurney

DOI: 10.1016/1044-7431(91)90009-D

关键词: NeuroscienceCancer researchMessenger RNATemporal lobe/cortexCiliary neurotrophic factorBiologyGene expressionHuman brainTemporal lobeNerve growth factorNeurotrophic factors

摘要: Expression of brain-derived neurotrophic factor (BDNF) and nerve growth (NGF) mRNA transcripts was studied in specimens from 10 human brain tumors normal brain. BDNF is a prevalent transcript frontal temporal lobe cortex, this expressed by all gliomas meningiomas examined. In contrast to the prevalence expression, NGF three eight one but not either studied. These data suggest that factors may play role variety tumors.

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