ProBDNF and its receptors are upregulated in glioma and inhibit the growth of glioma cells in vitro.

作者: J. Xiong , L. Zhou , M. Yang , Y. Lim , Y.-h. Zhu

DOI: 10.1093/NEUONC/NOT039

关键词:

摘要: … The expression levels of the BDNF gene, the NGFR (p75NTR) gene, and the SORT1 (sortilin) gene in both control brain tissues and gliomas of different malignancy grades were …

参考文章(86)
Takuya Akai, Kenji Niiya, Nobuo Sakuragawa, Hideaki Iizuka, Shunro Endo, Modulation of tissue-type plasminogen activator expression by platelet activating factor in human glioma cells. Journal of Neuro-oncology. ,vol. 59, pp. 193- 198 ,(2002) , 10.1023/A:1019966918589
Carla Weis, Bettina Wiesenhofer, Christian Humpel, Nerve growth factor plays a divergent role in mediating growth of rat C6 glioma cells via binding to the p75 neurotrophin receptor. Journal of Neuro-oncology. ,vol. 56, pp. 59- 67 ,(2002) , 10.1023/A:1014410519935
Eric C. Holland, Gliomagenesis: genetic alterations and mouse models Nature Reviews Genetics. ,vol. 2, pp. 120- 129 ,(2001) , 10.1038/35052535
Michael J. Winger, David R. Macdonald, J. Gregory Cairncross, Supratentorial anaplastic gliomas in adults. The prognostic importance of extent of resection and prior low-grade glioma. Journal of Neurosurgery. ,vol. 71, pp. 487- 493 ,(1989) , 10.3171/JNS.1989.71.4.0487
Adrian Merlo, Genes and pathways driving glioblastomas in humans and murine disease models. Neurosurgical Review. ,vol. 26, pp. 145- 158 ,(2003) , 10.1007/S10143-003-0267-8
M. Fahnestock, D. Garzon, R. M. D. Holsinger, B. Michalski, Neurotrophic factors and Alzheimer’s disease: are we focusing on the wrong molecule? Journal of Neural Transmission-supplement. pp. 241- 252 ,(2002) , 10.1007/978-3-7091-6139-5_22
David N. Louis, WHO classification of tumours of the central nervous system International Agency for Research on Cancer. ,(2007)