The Mortimer M. Bortin Lecture: to destroy by the reaction of immunity: the search for separation of graft-versus-leukemia and graft-versus-host.

作者: Robert L. Truitt

DOI: 10.1016/J.BBMT.2004.05.005

关键词: Immune systemImmunotherapyTransplantationMalignant diseaseLeukemiaImmunologyMedicineGraft vs Host ReactionSurgeryGraft-vs-Leukemia EffectImmunity

摘要: The graft-versus-leukemia effect of allogeneic blood or marrow transplantation is a dramatic example the power immune system to eradicate malignant disease. In this personal essay, adapted from inaugural Mortimer M. Bortin Lecture presented at 2004 Tandem BMT Meetings, author recounts early efforts by and others manipulate separate it potentially fatal complications graft-versus-host

参考文章(300)
D. W. H. Barnes, M. J. Corp, J. F. Loutit, F. E. Neal, Treatment of Murine Leukaemia with X Rays and Homologous Bone Marrow BMJ. ,vol. 2, pp. 626- 627 ,(1956) , 10.1136/BMJ.2.4993.626
E.Donnall Thomas, JosephW Ferrebee, IRRADIATION AND MARROW TRANSPLANTATION The Lancet. ,vol. 275, pp. 1289- 1290 ,(1960) , 10.1016/S0140-6736(60)92266-2
Loredana Ruggeri, Marusca Capanni, Myriam Casucci, Isabella Volpi, Antonella Tosti, Katia Perruccio, Elena Urbani, Robert S. Negrin, Massimo F. Martelli, Andrea Velardi, Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation. Blood. ,vol. 94, pp. 333- 339 ,(1999) , 10.1182/BLOOD.V94.1.333.413A31_333_339
Factors Modifying the Effect of X-Irradiation on Regression of a Transplanted Lymphosarcoma Journal of the National Cancer Institute. ,vol. 12, pp. 751- 763 ,(1952) , 10.1093/JNCI/12.4.751
HJ Kolb, J Mittermuller, C Clemm, E Holler, G Ledderose, G Brehm, M Heim, W Wilmanns, Donor Leukocyte Transfusions for Treatment of Recurrent Chronic Myelogenous Leukemia in Marrow Transplant Patients Blood. ,vol. 76, pp. 2462- 2465 ,(1990) , 10.1182/BLOOD.V76.12.2462.2462
S. Morecki, M. Weigensberg, S. Bar, R. Or, Z. Fuks, Z. Weshler, S. Slavin, L. Weiss, The use of total lymphoid irradiation for allogeneic bone marrow transplantation in animals and man Survey of immunologic research. ,vol. 4, pp. 238- 252 ,(1985) , 10.1007/BF02918677
Effects of ionizing radiations on a transplanted lymphosarcoma. Journal of the National Cancer Institute. ,vol. 11, pp. 1- 16 ,(1950) , 10.1093/JNCI/11.1.1