Immune function in cigarette smokers who quit smoking for 31 days

摘要: A group of 28 healthy, white, male, light-to-moderate smokers, 21 to 35 years age, were offered a financial inducement abstain from smoking for 31 days. matched control 11 smokers paid continue during the same period. Nonspecific parameters immune system function monitored before and at various times after abstinence. Abstinence increased natural killer cell cytotoxic activity but did not alter mitogen-induced T-lymphocyte proliferation as measured by responses concanavalin or phytohemagglutinin. Serum cortisol concentrations also decreased cessation; however, changes in correlated with serum change, nor indices such plasma nicotine cotinine levels. Responses phytohemagglutinin positively change self-reported alcohol ingestion Results indicate that elevation kill is detectable within 1 month cessation, even smokers. However, appears be directly related cessation-induced reductions nicotine, cotinine, circulating