ANTIBODY-DRUG CONJUGATE COMPRISING ANTIBODY AGAINST HUMAN ROR1 AND USE FOR THE SAME
作者： Kim Yong Zu , Song Ho Young , Lee Yangsoon , Lee Bora , Ahn Jinhyung
DOI:
关键词: ROR1 、 Conjugate 、 Pharmacology 、 Chemistry 、 Antibody 、 Antibody-drug conjugate
摘要: The present invention relates to new antibody-drug conjugates (ADCs) targeting ROR1, active metabolites of such ADCs, methods for preparation uses ADCs in treatment and/or prevention illnesses, and production drugs diseases, more specifically diseases associated with over-expression example cancer. More specifically, the an conjugate comprising antibody that binds ROR1 or antigen-binding fragment thereof, a pharmaceutical composition same.
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