Anti-ror1 antibodies

作者: Christian Rohlff , Jonathan Alexander Terrett , Alasdair Stamps

DOI:

关键词:

摘要: The invention provides antibodies which bind to the extracellular domain of Tyrosine-protein kinase transmembrane receptor ROR1. Nucleic acid molecules encoding antibodies, expression vectors, host cells and methods for expressing are also provided. may be used treatment cancer, including non-small cell lung carcinoma, B-cell chronic lymphocytic leukemia colon cancer.

参考文章(125)
Markus Warmuth, Karin Foster, Ror1 as a therapeutic target for lung cancer ,(2007)
G. M. Grass, J. R. Robinson, Sustained- and controlled-release drug delivery systems Drugs and the pharmaceutical sciences. ,vol. 40, pp. 635- 671 ,(1978)
Carl-Wilhelm Vogel, Immunoconjugates : antibody conjugates in radioimaging and therapy of cancer Oxford University Press. ,(1987)
Sivasubramanian Baskar, Christoph Rader, Anti-human ror1 antibodies ,(2010)
Patrick Henry Beusker, Franciscus Marinus Hendrikus De Groot, Triazole-Containing Releasable Linkers, Conjugates Thereof, and Methods of Preparation ,(2006)
Emmanuel Pitsinos, Adrian L. Smith, Kyriacos C. Nicolaou, Chan-Kou Hwang, Analogs of calicheamicin gamma1I, method of making and using the same ,(1992)