Antiangiogene Therapie in Kombination mit Temozolomid beim experimentellen MGMT-methylierten Glioblastom

Bettina Grasl Kraupp, Branislav Ruttkay-Nedecky, Helga Koudelka, Krystyna Bukowska, Wilfried Bursch, Rolf Schulte-Hermann, In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note Hepatology. ,vol. 21, pp. 1465- 1468 ,(1995) , 10.1002/HEP.1840210534

Nils Ole Schmidt, Manfred Westphal, Christian Hagel, S�leyman Erg�n, Dimitrios Stavrou, Eliot M. Rosen, Katrin Lamszus, Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis International Journal of Cancer. ,vol. 84, pp. 10- 18 ,(1999) , 10.1002/(SICI)1097-0215(19990219)84:1<10::AID-IJC3>3.0.CO;2-L

Frank Winkler, Sergey V. Kozin, Ricky T. Tong, Sung-Suk Chae, Michael F. Booth, Igor Garkavtsev, Lei Xu, Daniel J. Hicklin, Dai Fukumura, Emmanuelle di Tomaso, Lance L. Munn, Rakesh K. Jain, Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell. ,vol. 6, pp. 553- 563 ,(2004) , 10.1016/J.CCR.2004.10.011

Giannoula Klement, Sylvain Baruchel, Janusz Rak, Shan Man, Katherine Clark, Daniel J. Hicklin, Peter Bohlen, Robert S. Kerbel, Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity Journal of Clinical Investigation. ,vol. 105, pp. 2827- 2827 ,(2000) , 10.1172/JCI8829

Alan H. Shih, Eric C. Holland, Platelet-derived growth factor (PDGF) and glial tumorigenesis. Cancer Letters. ,vol. 232, pp. 139- 147 ,(2006) , 10.1016/J.CANLET.2005.02.002

Peter Carmeliet, Rakesh K. Jain, Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases Nature Reviews Drug Discovery. ,vol. 10, pp. 417- 427 ,(2011) , 10.1038/NRD3455

Amber N. Stratman, Kristine M. Malotte, Rachel D. Mahan, Michael J. Davis, George E. Davis, Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood. ,vol. 114, pp. 5091- 5101 ,(2009) , 10.1182/BLOOD-2009-05-222364

Michael Weller, Roger Stupp, Guido Reifenberger, Alba A. Brandes, Martin J. van den Bent, Wolfgang Wick, Monika E. Hegi, MGMT promoter methylation in malignant gliomas: ready for personalized medicine? Nature Reviews Neurology. ,vol. 6, pp. 39- 51 ,(2010) , 10.1038/NRNEUROL.2009.197

Ping Guo, Bo Hu, Weisong Gu, Li Xu, Degui Wang, Hui-Jen Su Huang, Webster K. Cavenee, Shi-Yuan Cheng, Platelet-Derived Growth Factor-B Enhances Glioma Angiogenesis by Stimulating Vascular Endothelial Growth Factor Expression in Tumor Endothelia and by Promoting Pericyte Recruitment American Journal of Pathology. ,vol. 162, pp. 1083- 1093 ,(2003) , 10.1016/S0002-9440(10)63905-3

Teresa Ribalta, Ian E McCutcheon, Kenneth D Aldape, Janet M Bruner, Gregory N Fuller, The mitosis-specific antibody anti-phosphohistone-H3 (PHH3) facilitates rapid reliable grading of meningiomas according to WHO 2000 criteria. The American Journal of Surgical Pathology. ,vol. 28, pp. 1532- 1536 ,(2004) , 10.1097/01.PAS.0000141389.06925.D5