MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

作者: Michael Weller , Roger Stupp , Guido Reifenberger , Alba A. Brandes , Martin J. van den Bent

DOI: 10.1038/NRNEUROL.2009.197

关键词:

摘要: … (MGMT) antagonizes the genotoxic effects of alkylating agents. MGMT promoter methylation is the key mechanism of MGMT … , the relevance of MGMT promoter methylation might extend …

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