作者: Giovanna Fragneto , Frank Gabel
DOI: 10.1140/EPJE/I2013-13081-4
关键词: Chemical physics 、 Biological small-angle scattering 、 Neutron diffraction 、 Physics 、 Membrane raft 、 Neutron spectroscopy 、 Neutron spin echo 、 Chloroplast thylakoid 、 Neutron 、 Neutron scattering 、 Nanotechnology
摘要: This special issue brings together a number of original research papers focused on recent developments in biological membrane and model studies by variety state-of-the-art biophysical methods. Neutron scattering is especially well represented. Our knowledge macromolecules their interactions based the application physical methods, ranging from classical thermodynamics to recently developed techniques for detection manipulation single molecules. The role neutron diffraction spectroscopy improving this has been outstanding potential future remarkable. Many challenges remain answer questions raised molecular cellullar biology. following pages give flavour progress field. A report [1] describes time-resolved small angle light-induced changes chloroplast thylakoid membranes. In context surface functionalization, structure different ionic conditions sodium hyaluronan grafted at solid-liquid interface was observed reflectivity [2]. review protein [3] addresses difficulties encountered providing information properties surfactants used solubilise proteins contrast variation scattering, as deuterium labelling strategies. thought-provoking Zaccai resilience site-specific hydration dynamics globular are discussed [4]. Membrane raft structures with tuneable compositions were characterised [5], while large uni-lamellar vesicles interaction beta amyloid peptide spin echo method combined [6]. bending stiffness membranes determined also presented [7]. Two contributions [8, 9] undulation shape fluctuations, respectively, lipid function composition other parameters combination methods like light scattering. Elastic incoherent applied compare natural extracted hyperthermophile mesophile bacteria activities [10]. simulation study discusses macromolecular defined experiments. underlying mechanisms bioprotection sugars explored using data Infrared Spectroscopy, Molecular Dynamics simulations, Small Angle X-ray Scattering Calorimetry [11]. Time resolved can contribute immensely paper presents new set-up, including microfluidic continuous-flow mixer, which provided results unfolding dynamics. And project bank Perspectives article [12]. aim will be make systems widely available scientific community.