Editorial on the topical issue "neutron biological physics".

作者: Giovanna Fragneto , Frank Gabel

DOI: 10.1140/EPJE/I2013-13081-4

关键词: Chemical physicsBiological small-angle scatteringNeutron diffractionPhysicsMembrane raftNeutron spectroscopyNeutron spin echoChloroplast thylakoidNeutronNeutron scatteringNanotechnology

摘要: This special issue brings together a number of original research papers focused on recent developments in biological membrane and model studies by variety state-of-the-art biophysical methods. Neutron scattering is especially well represented. Our knowledge macromolecules their interactions based the application physical methods, ranging from classical thermodynamics to recently developed techniques for detection manipulation single molecules. The role neutron diffraction spectroscopy improving this has been outstanding potential future remarkable. Many challenges remain answer questions raised molecular cellullar biology. following pages give flavour progress field. A report [1] describes time-resolved small angle light-induced changes chloroplast thylakoid membranes. In context surface functionalization, structure different ionic conditions sodium hyaluronan grafted at solid-liquid interface was observed reflectivity [2]. review protein [3] addresses difficulties encountered providing information properties surfactants used solubilise proteins contrast variation scattering, as deuterium labelling strategies. thought-provoking Zaccai resilience site-specific hydration dynamics globular are discussed [4]. Membrane raft structures with tuneable compositions were characterised [5], while large uni-lamellar vesicles interaction beta amyloid peptide spin echo method combined [6]. bending stiffness membranes determined also presented [7]. Two contributions [8, 9] undulation shape fluctuations, respectively, lipid function composition other parameters combination methods like light scattering. Elastic incoherent applied compare natural extracted hyperthermophile mesophile bacteria activities [10]. simulation study discusses macromolecular defined experiments. underlying mechanisms bioprotection sugars explored using data Infrared Spectroscopy, Molecular Dynamics simulations, Small Angle X-ray Scattering Calorimetry [11]. Time resolved can contribute immensely paper presents new set-up, including microfluidic continuous-flow mixer, which provided results unfolding dynamics. And project bank Perspectives article [12]. aim will be make systems widely available scientific community.

参考文章(12)
Cécile Breyton, Frank Gabel, Mathilde Lethier, Ali Flayhan, Grégory Durand, Jean-Michel Jault, Céline Juillan-Binard, Lionel Imbert, Martine Moulin, Stéphanie Ravaud, Michael Härtlein, Christine Ebel, Small angle neutron scattering for the study of solubilised membrane proteins. European Physical Journal E. ,vol. 36, pp. 71- 71 ,(2013) , 10.1140/EPJE/I2013-13071-6
Ida Berts, Giovanna Fragneto, Jöns Hilborn, Adrian R. Rennie, Tuning the density profile of surface-grafted hyaluronan and the effect of counter-ions. European Physical Journal E. ,vol. 36, pp. 70- 70 ,(2013) , 10.1140/EPJE/I2013-13070-7
Gergely Nagy, László Kovács, Renáta Ünnep, Ottó Zsiros, László Almásy, László Rosta, Peter Timmins, Judith Peters, Dorthe Posselt, Győző Garab, Kinetics of structural reorganizations in multilamellar photosynthetic membranes monitored by small-angle neutron scattering European Physical Journal E. ,vol. 36, pp. 69- 80 ,(2013) , 10.1140/EPJE/I2013-13069-0
Leonid Rusevich, Victoria García Sakai, Bruno Franzetti, Mark Johnson, Francesca Natali, Eric Pellegrini, Judith Peters, Jörg Pieper, Martin Weik, Giuseppe Zaccai, Perspectives in biological physics: The nDDB project for a neutron Dynamics Data Bank for biological macromolecules European Physical Journal E. ,vol. 36, pp. 80- 80 ,(2013) , 10.1140/EPJE/I2013-13080-5
V. Rondelli, E. Del Favero, S. Motta, L. Cantù, G. Fragneto, P. Brocca, Neutrons for rafts, rafts for neutrons European Physical Journal E. ,vol. 36, pp. 73- 73 ,(2013) , 10.1140/EPJE/I2013-13073-4
Mitushiro Hirai, Ryota Kimura, Kazuki Takeuchi, Masaaki Sugiyama, Kouji Kasahara, Noboru Ohta, Bela Farago, Andreas Stadler, Giuseppe Zaccai, Change of dynamics of raft-model membrane induced by amyloid-β protein binding European Physical Journal E. ,vol. 36, pp. 74- ,(2013) , 10.1140/EPJE/I2013-13074-3
Yinglong Miao, Liang Hong, Zheng Yi, Jeremy C. Smith, Zaccai neutron resilience and site-specific hydration dynamics in a globular protein European Physical Journal E. ,vol. 36, pp. 72- ,(2013) , 10.1140/EPJE/I2013-13072-5
Michael Mell, Lara H. Moleiro, Yvonne Hertle, Peter Fouquet, Ralf Schweins, Iván López-Montero, Thomas Hellweg, Francisco Monroy, Bending stiffness of biological membranes: What can be measured by neutron spin echo? European Physical Journal E. ,vol. 36, pp. 75- 75 ,(2013) , 10.1140/EPJE/I2013-13075-2