Regulation of BCRP/ABCG2 expression by progesterone and 17β-estradiol in human placental BeWo cells
作者： Honggang Wang , Lin Zhou , Anshul Gupta , R. Robert Vethanayagam , Yi Zhang
DOI: 10.1152/AJPENDO.00397.2005
关键词: Placenta 、 Chemistry 、 Abcg2 、 Internal medicine 、 Cell culture 、 Regulation of gene expression 、 Receptor 、 Endocrinology 、 Fulvestrant 、 Hormone 、 Fetus
摘要: The breast cancer resistance protein (BCRP) is abundant in the placenta and protects fetus by limiting placental drug penetration. We hypothesize that pregnancy-specific hormones regulate BCRP ...
sci-hub.se 参考文章(36)
Tito Fojo, Lyn Mickley, Susan E. Bates, Mariafiorella Brangi, Barbara Cristensen, Robert Robey, Michael Dean, Keisuke Miyake, Zhirong Zhan, Thomas Litman, Lee Greenberger, Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes. Cancer Research. ,vol. 59, pp. 8- 13 ,(1999)
I F Faneyte, A C Pijnenborg, J H Schellens, M Maliepaard, G L Scheffer, M J van De Vijver, A H Schinkel, R J Scheper, M A van Gastelen, Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Research. ,vol. 61, pp. 3458- 3464 ,(2001)
Talal El-Hefnawy, Pulak R. Manna, Michaela Luconi, Elizabetta Baldi, J. Peter Slotte, Ilpo Huhtaniemi, Progesterone Action in a Murine Leydig Tumor Cell Line (mLTC-1), Possibly through a Nonclassical Receptor Type1 Endocrinology. ,vol. 141, pp. 247- 255 ,(2000) , 10.1210/ENDO.141.1.7253
Pauline Breedveld, Noam Zelcer, Dick Pluim, Özgür Sönmezer, Matthijs M. Tibben, Jos H. Beijnen, Alfred H. Schinkel, Olaf van Tellingen, Piet Borst, Jan H. M. Schellens, Mechanism of the Pharmacokinetic Interaction between Methotrexate and Benzimidazoles: Potential Role for Breast Cancer Resistance Protein in Clinical Drug-Drug Interactions Cancer Research. ,vol. 64, pp. 5804- 5811 ,(2004) , 10.1158/0008-5472.CAN-03-4062
SHI-WEN JIANG, RICARDO V. LLOYD, LONG JIN, NORMAN L. EBERHARDT, Estrogen receptor expression and growth-promoting function in human choriocarcinoma cells DNA and Cell Biology. ,vol. 16, pp. 969- 977 ,(1997) , 10.1089/DNA.1997.16.969
Anshul Gupta, Yi Zhang, Jashvant D. Unadkat, Qingcheng Mao, HIV Protease Inhibitors Are Inhibitors but Not Substrates of the Human Breast Cancer Resistance Protein (BCRP/ABCG2) Journal of Pharmacology and Experimental Therapeutics. ,vol. 310, pp. 334- 341 ,(2004) , 10.1124/JPET.104.065342
A Suvannasankha, H Minderman, K L O'Loughlin, T Nakanishi, W R Greco, D D Ross, M R Baer, Breast cancer resistance protein (BCRP/MXR/ABCG2) in acute myeloid leukemia: discordance between expression and function. Leukemia. ,vol. 18, pp. 1252- 1257 ,(2004) , 10.1038/SJ.LEU.2403395
Yuji Tanaka, Angela L. Slitt, Tyra M. Leazer, Jonathan M. Maher, Curtis D. Klaassen, Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice. Biochemical and Biophysical Research Communications. ,vol. 326, pp. 181- 187 ,(2004) , 10.1016/J.BBRC.2004.11.012
Kimberly J. Bailey-Dell, Bret Hassel, L.Austin Doyle, Douglas D. Ross, Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene Biochimica et Biophysica Acta. ,vol. 1520, pp. 234- 241 ,(2001) , 10.1016/S0167-4781(01)00270-6
SATISH BATRA, LARS PHILIP BENGTSSON, 17β-Estradiol and Progesterone Concentrations in Myometrium of Pregnancy and Their Relationships to Concentrations in Peripheral Plasma The Journal of Clinical Endocrinology and Metabolism. ,vol. 46, pp. 622- 626 ,(1978) , 10.1210/JCEM-46-4-622