Variations in serum concentrations of selected organochlorines among delivering women in Argentina. The EMASAR study.

作者: Solrunn Hansen , Evert Nieboer , Natalia Bravo , Inger Økland , Silvinia Matiocevich

DOI: 10.1039/C7EM00278E

关键词: Serum samplesParity (mathematics)Animal scienceBiologyRegional differencesSerum concentrationDetection rateLifestyle factorsDichlorodiphenyl DichloroethyleneEnvironmental protectionThe arctic

摘要: The EMASAR study is the first to describe body burden of OCs in Argentinian women after delivery. In total, 698 maternal serum samples from Salta (n = 498) and Ushuaia 200) were collected 2011–2012 analyzed for a total 7 polychlorinated biphenyls (PCBs) 12 pesticide-related compounds. Only 11 compounds had detection rates above 60% one or both places. Compared with Ushuaian women, those exhibited higher lipid-adjusted concentrations p,p′-DDE, p,p′-DDT, β-HCH, PCB 118 (p ≤ 0.003), no differences 153 138. After controlling age, parity heritage (born province migrated there other regions Argentina), β-HCH all PCBs significantly natives compared migrants 0.010). No variations between native observed than (6.1 versus 8.6 μg kg−1 lipid, p 0.022). Age was generally associated positively nearly negatively so, p,p′-DDD, o,p′-DDT, o,p′-DDD residues α-HCH being exceptions. regional OC are explained by contrasting domestic sources, historical current uses, industrial emissions, dietary patterns lifestyle factors, as well long-range-transport. relatively high 118/PCB 180 ratio communities likely reflects use technical mixtures congener-specific composition. comprehensive comparison countries, mostly lower range. It concluded that latitude effect equivalent operative Arctic region seems unlikely.

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