Food intake and serum persistent organic pollutants in the Greenlandic pregnant women: The ACCEPT sub-study

作者: Manhai Long , Ane-Kersti Skaarup Knudsen , Henning Sloth Pedersen , Eva Cecilie Bonefeld-Jørgensen

DOI: 10.1016/J.SCITOTENV.2015.05.022

关键词:

摘要: The Greenlandic Inuit have high blood concentrations of environmental persistent organic pollutants (POPs). High POP been associated with age, smoking and consumption marine mammals. Studies indicated that exposure to POPs during pregnancy may adversely affect fetal child development. To assess geographical differences in diet, lifestyle contaminant among pregnant women Greenland, samples questionnaire data were collected from 207 five regions (North, Disco Bay, West, South East). Blood analyzed for 11 organochlorine pesticides (OCPs), 14 polychlorinated biphenyls (PCBs), 5 polybrominated diphenyl ethers (PBDEs), 15 perfluoroalkylated substances (PFASs) 63 metals. A trend higher intake mammals the East North was reflected by a n-3/n-6 fatty acid ratio. Participants region tended also terrestrial species. significant seabird seen West region. Significant regional found PCBs, OCPs, PFASs mercury, levels regions. significantly PCBs OCPs most In region, both selenium mercury. No difference observed PBDEs. mercury related traditional food. Compared earlier reports, decreased legacy POPs, Hg Pb perfluorooctane sulfonate perfluorooctanoic observed, but PFAS congeners perfluorohexane perfluorononanoic sustained. detection heavy metals maternal indicates these compounds possibly influencing

参考文章(65)
Stefan Posner, , Sandra Roos, Pia Brunn Poulsen, Hrönn Ólína Jörundsdottir, Helga Gunnlaugsdóttir, Xenia Trier, Allan Astrup Jensen, Athanasios A. Katsogiannis, Dorte Herzke, Eva Cecilie Bonefeld-Jörgensen, Christina Jönsson, Gitte Alsing Pedersen, Mandana Ghisari, Sophie Jensen, Per- and polyfluorinated substances in the Nordic Countries : Use, occurence and toxicology Nordic Council of Ministers. ,(2013) , 10.6027/TN2013-542
Britta Fängström, Maria Athanasiadou, Philippe Grandjean, Pál Weihe, Åke Bergman, Hydroxylated PCB metabolites and PCBs in serum from pregnant Faroese women. Environmental Health Perspectives. ,vol. 110, pp. 895- 899 ,(2002) , 10.1289/EHP.02110895
Bente Deutch, Jørn Dyerberg, Henning Sloth Pedersen, Ejner Aschlund, Jens C. Hansen, Traditional and modern Greenlandic food — Dietary composition, nutrients and contaminants Science of The Total Environment. ,vol. 384, pp. 106- 119 ,(2007) , 10.1016/J.SCITOTENV.2007.05.042
J BUTLERWALKER, L SEDDON, E MCMULLEN, J HOUSEMAN, K TOFFLEMIRE, A CORRIVEAU, J WEBER, C MILLS, S SMITH, J VANOOSTDAM, Organochlorine levels in maternal and umbilical cord blood plasma in Arctic Canada. Science of The Total Environment. ,vol. 302, pp. 27- 52 ,(2003) , 10.1016/S0048-9697(02)00319-4
B DEUTCH, H PEDERSEN, G ASMUND, J HANSEN, Contaminants, diet, plasma fatty acids and smoking in Greenland 1999-2005. Science of The Total Environment. ,vol. 372, pp. 486- 496 ,(2007) , 10.1016/J.SCITOTENV.2006.10.043
G ASMUND, K VORKAMP, S BACKUS, M COMBA, An update on analytical methods, quality assurance and quality control used in the Greenland AMAP programme: 1999-2002. Science of The Total Environment. ,vol. 331, pp. 233- 245 ,(2004) , 10.1016/J.SCITOTENV.2004.03.031
Alexander G. Paul, Kevin C. Jones, Andrew J. Sweetman, A first global production, emission and environmental inventory for perfluorooctane sulfonate. Environmental Science & Technology. ,vol. 43, pp. 386- 392 ,(2009) , 10.1021/ES802216N
Philippe Grandjean, Elisabeth Wreford Andersen, Esben Budtz-Jørgensen, Flemming Nielsen, Kåre Mølbak, Pal Weihe, Carsten Heilmann, Serum Vaccine Antibody Concentrations in Children Exposed to Perfluorinated Compounds JAMA. ,vol. 307, pp. 391- 397 ,(2012) , 10.1001/JAMA.2011.2034
Sonja K. Ostertag, Brett A. Tague, Murray M. Humphries, Sheryl A. Tittlemier, Hing Man Chan, Estimated dietary exposure to fluorinated compounds from traditional foods among Inuit in Nunavut, Canada. Chemosphere. ,vol. 75, pp. 1165- 1172 ,(2009) , 10.1016/J.CHEMOSPHERE.2009.02.053
Anna Sofía Veyhe, Dag Hofoss, Solrunn Hansen, Yngvar Thomassen, Torkjel M. Sandanger, Jon Øyvind Odland, Evert Nieboer, The Northern Norway Mother-and-Child Contaminant Cohort (MISA) Study: PCA analyses of environmental contaminants in maternal sera and dietary intake in early pregnancy. International Journal of Hygiene and Environmental Health. ,vol. 218, pp. 254- 264 ,(2015) , 10.1016/J.IJHEH.2014.12.001