Contaminants, diet, plasma fatty acids and smoking in Greenland 1999-2005.

作者: B DEUTCH , H PEDERSEN , G ASMUND , J HANSEN

DOI: 10.1016/J.SCITOTENV.2006.10.043

关键词:

摘要: Abstract Objectives The purpose of this study is to monitor and assess human exposure pollution in the Arctic which presents a potential future health risk for local populations. Epidemiological studies Greenland have shown that blood levels several organic contaminants are very high, especially North where people depend on food. In East (Ittoqqortoormiit (Scoresbysund)) population shows highest persistent pollutants found countries, PCB, exceed Canadian guideline levels. As other predominant source these diet. However, factors such as smoking may influence metabolism thereby accumulation toxic substances. Study design This project part program ongoing circumpolar “Artic Monitoring Assessment Programme”. Lifestyle, anthropometric factors, dietary survey results covering 500 men women from 6 Greenlandic districts were analyzed along with lipids, fatty acid profiles, heavy metals concentrations (POPs). Results showed traditional food average provided 20–30% total energy intake. relative monthly meal intake seal, whale, polar bear, fish game, composition imported food, varied between districts. Seal bear intake, and, particular all plasma n-3 acids, significantly correlated contaminant concentrations, (betaHCH, chlordanes, DDTs, Hexachlorobenzene, Mirex, PCBs, toxaphenes) p ⁎⁎ . After adjusting age, district, or was high above mentioned POPs. Conclusion main predictors male gender, n-3/n-6 ratio marker marine mammals.

参考文章(21)
Robert W. Furness, Heavy metals in the marine environment. CRC Press. pp. 1- 4 ,(2018) , 10.1201/9781351073158
P Marckmann, A Lassen, J Haraldsdóttir, B Sandström, Biomarkers of habitual fish intake in adipose tissue. The American Journal of Clinical Nutrition. ,vol. 62, pp. 956- 959 ,(1995) , 10.1093/AJCN/62.5.956
Jean Lagueux, Daria Pereg, Pierre Ayotte, Eric Dewailly, Guy G. Poirier, Cytochrome P450 CYP1A1 enzyme activity and DNA adducts in placenta of women environmentally exposed to organochlorines. Environmental Research. ,vol. 80, pp. 369- 382 ,(1999) , 10.1006/ENRS.1998.3920
D SAINTAMOUR, M ROY, C BASTIEN, P AYOTTE, E DEWAILLY, C DESPRES, S GINGRAS, G MUCKLE, Alterations of visual evoked potentials in preschool Inuit children exposed to methylmercury and polychlorinated biphenyls from a marine diet. Neurotoxicology. ,vol. 27, pp. 567- 578 ,(2006) , 10.1016/J.NEURO.2006.02.008
J Van Oostdam, A Gilman, E Dewailly, P Usher, B Wheatley, H Kuhnlein, S Neve, J Walker, B Tracy, M Feeley, V Jerome, B Kwavnick, Human health implications of environmental contaminants in Arctic Canada: A review Science of The Total Environment. ,vol. 230, pp. 1- 82 ,(1999) , 10.1016/S0048-9697(99)00036-4
Florence Caurant, Miguel Navarro, Amiard, Jean-Claude, Mercury in pilot whales: possible limits to the detoxification process Science of The Total Environment. ,vol. 186, pp. 95- 104 ,(1996) , 10.1016/0048-9697(96)05087-5
Pietro Apostoli, Michele Magoni, Roberto Bergonzi, Sergio Carasi, Anna Indelicato, Carmelo Scarcella, Francesco Donato, Assessment of reference values for polychlorinated biphenyl concentration in human blood. Chemosphere. ,vol. 61, pp. 413- 421 ,(2005) , 10.1016/J.CHEMOSPHERE.2005.02.034
Pierre Ayotte, Éric Dewailly, George H. Lambert, Sherry L. Perkins, Raymond Poon, Mark Feeley, Christian Larochelle, Daria Pereg, Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines. Environmental Health Perspectives. ,vol. 113, pp. 1318- 1324 ,(2005) , 10.1289/EHP.7970
P JOHANSEN, T PARS, P BJERREGAARD, Lead, cadmium, mercury and selenium intake by Greenlanders from local marine food. Science of The Total Environment. ,vol. 245, pp. 187- 194 ,(2000) , 10.1016/S0048-9697(99)00443-X