Assessing determinants of maternal blood concentrations for persistent organic pollutants and metals in the eastern and western Canadian Arctic

摘要: Abstract Aboriginal peoples in the Canadian Arctic are exposed to persistent organic pollutants (POPs) and metals mainly through their consumption of a traditional diet wildlife items. Recent studies indicate that many human chemical levels have decreased north, likely due combination reduced global emissions, dietary shifts, risk mitigation efforts by local health authorities. Body burdens for chemicals mothers can be further offset breastfeeding, parity, other maternal characteristics. We assessed impact several covariates following decade awareness contaminant issue northern Canada, performing multiple stepwise linear regression analyses from blood concentrations demographic variables 176 recruited Nunavut Northwest Territories during period 2005–2007. A significant aboriginal group effect was observed modeled chemicals, except lead cadmium, after adjusting covariates. Further, POPs were significantly associated with at least one covariate older age, fewer months spent more frequent eating foods, or smoking pregnancy. Cadmium had highest explained variance (72.5%) just two (current status parity). Although Inuit participants consumed foods general, coastal communities continued demonstrate higher adjusted examined here. While this is part prevalence marine mammals eastern diet, it possible effects unrelated may also contribute elevated body populations.