High-dose dexmedetomidine increases the opioid-free interval and decreases opioid requirement after tonsillectomy in children.
作者： Sophie R. Pestieau , Zenaide M. N. Quezado , Yewande J. Johnson , Jennifer L. Anderson , Yao I. Cheng
DOI: 10.1007/S12630-011-9493-7
关键词: Morphine 、 Anesthesia 、 Opioid 、 Dexmedetomidine 、 Sedative 、 Analgesic 、 Tonsillectomy 、 Medicine 、 Fentanyl 、 Agonist
摘要: Purpose Dexmedetomidine, a selective α2 adrenoreceptor agonist, has analgesic and sedative properties, minimal impact on respiratory parameters, reportedly decreases requirements after surgery. Given its pharmacodynamic profile, dexmedetomidine might have role for postoperative pain control in children undergoing tonsillectomy. In this study, we hypothesized that would delay decrease opioid
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