Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy

作者: Levi A. Garraway , Cory M. Johannessen

DOI:

关键词: Combination therapyCancer therapyHDAC inhibitorMAPK/ERK pathwayIn patientCancerMEK inhibitorPharmacologyMedicineTreatment method

摘要: A method of identifying a subject having cancer who is likely to benefit from treatment with combination therapy MAPK pathway inhibitor, such as RAF MEK or ERK and GEF HDAC inhibitor provided. treating in need thereof also provided includes administering the an effective amount inhibitor. targets that confers resistance

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