Optimal strategies in immunology III. The IgM-IgG switch
作者： Alan S. Perelson , Byron Goldstein , Sol Rocklin
DOI: 10.1007/BF00276984
关键词: Virology 、 Immunoglobulin heavy chain 、 Immunoglobulin M 、 Biology 、 Secondary immune response 、 Immunology 、 Primary immune response 、 Immunoglobulin class switching 、 Antibody 、 Antigen 、 Immunoglobulin G
摘要: During a primary immune response generally two classes of antibody are produced, immunoglobulin M (IgM) and G (IgG). It is currently thought that some lymphocytes which initially produce IgM switch to the production IgG with same specificity for antigen. secondary predominant made throughout response. In this paper we address question why such apparently complicated modes should have been adapted by evolution.
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