Recent advances and clinical insights into the use of proteomics in the study of atherosclerosis
作者： Laura Mourino-Alvarez , Montserrat Baldan-Martin , Raul Rincon , Tatiana Martin-Rojas , Nerea Corbacho-Alonso
DOI: 10.1080/14789450.2017.1353912
关键词: Bioinformatics 、 Diagnostic biomarker 、 Proteomics methods 、 Proteomics 、 Computational biology 、 Risk stratification 、 Biology
摘要: ABSTRACTIntroduction: The application of new proteomics methods may help to identify diagnostic/predictive molecular markers in an attempt improve the clinical management atherosclerosis.Areas covered: Technological advances have enhanced its sensitivity and multiplexing capacity, as well possibility studying protein interactions tissue structure. These will us better understand mechanisms at play atherosclerosis a biological system. Moreover, this should predictive/diagnostic biomarkers therapeutic targets that facilitate effective risk stratification early diagnosis, with ensuing rapid implementation treatment. This review provides comprehensive overview novel proteomics, including state-of-the-art techniques, samples applications for study atherosclerosis.Expert commentary: Collaboration between clinicians researchers is crucial further vali...
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