The inhibitory effect of IgM RF on the release of lysosomal substances.
作者： Ragnhild Gullberg , Renée Norberg
DOI: 10.3109/03009747609099904
关键词: Granulocyte 、 Vitamin 、 Inhibitory effect 、 Cytochalasin B 、 Molecular size 、 Biology 、 Biochemistry
摘要: Isolated IgM RF inhibited the IgG-induced release of lysosomal substances, measured as ‘large molecular size vitamin B12-binding protein’ (LBP) and β-glucuronidase, from separated human granulocytes. The effect was most marked when cytochalasin B added to experimental system. results indicate that RFs interact with granulocyte binding region IgG.
sci-hub.se 参考文章(19)
A Böyum, Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scandinavian Journal of Clinical & Laboratory Investigation. ,vol. 97, pp. 77- 89 ,(1968)
Mitsuo Sugiura, Shunji Futagawa, Fumio Shima, Soroku Ichihara, Masanobu Ishida, Esophageal transection with paraesophagogastric devascularization: surgical treatment of esophageal varices Gastroenterologia Japonica. ,vol. 9, pp. 23- 28 ,(1974) , 10.1007/BF02892451
Louis J. Ignarro, Release of Neutral Protease and β-Glucuronidase from Human Neutrophils in the Presence of Cartilage Treated with Various Immunologic Reactants Journal of Immunology. ,vol. 113, pp. 298- 308 ,(1974)
P. A. Ward, N. J. Zvaifler, Quantitative phagocytosis by neutrophils. II. Release of the C5-cleaving enzyme and inhibition of phagocytosis by rheumatoid factor. Journal of Immunology. ,vol. 111, pp. 1777- 1782 ,(1973)
Kunio Yonemasu, Robert M. Stroud, C1q: Rapid Purification Method for Preparation of Monospecific Antisera and for Biochemical Studies Journal of Immunology. ,vol. 106, pp. 304- 313 ,(1971)
Gerald Weissmann, Robert B. Zurier, Paul J. Spieler, Ira M. Goldstein, Mechanisms of lysosomal enzyme release from leukocytes exposed to immune complexes and other particles. Journal of Experimental Medicine. ,vol. 134, pp. 149- 165 ,(1971) , 10.1084/JEM.134.3.149
Ragnhild Gullberg, Vitamin B12-binding proteins in blood plasma and synovial fluid in arthritis. Scandinavian Journal of Rheumatology. ,vol. 1, pp. 129- 135 ,(1972) , 10.3109/03009747209103012
D A Lawrence, W O Weigle, H L Spiegelberg, Immunoglobulins cytophilic for human lymphocytes, monocytes, and neutrophils. Journal of Clinical Investigation. ,vol. 55, pp. 368- 376 ,(1975) , 10.1172/JCI107940
Robert B. Zurier, Gerald Weissmann, Sylvia Hoffstein, Sandra Kammerman, Hsin Hsiung Tai, Mechanisms of Lysosomal Enzyme Release from Human Leukocytes II. EFFECTS OF cAMP AND cGMP, AUTONOMIC AGONISTS, AND AGENTS WHICH AFFECT MICROTUBULE FUNCTION Journal of Clinical Investigation. ,vol. 53, pp. 297- 309 ,(1974) , 10.1172/JCI107550
G. Torrigiani, I.M. Roitt, K.N. Lloyd, Mary Corbett, Elevated IgG antiglobulins in patients with seronegative rheumatoid arthritis. The Lancet. ,vol. 295, pp. 14- 16 ,(1970) , 10.1016/S0140-6736(70)90524-6