INTEGRIN EXPRESSION BY HUMAN ARTICULAR CHONDROCYTES

作者： D. M. SALTER , D. E. HUGHES , R. SIMPSON , D. L. GARDNER

关键词: Cell adhesion 、 In vivo 、 Alpha (ethology) 、 Beta (finance) 、 Integrin 、 Monoclonal antibody 、 Chondrocyte 、 Cell biology 、 Beta-1 adrenergic receptor 、 Medicine 、 Anatomy

摘要: Expression of integrins, a family cell adhesion proteins, by human articular cartilage chondrocytes in vivo has been studied immunohistological techniques using cryostat sections and panel anti-integrin monoclonal antibodies. Chondrocytes strongly expressed beta 1 alpha 5 integrin subunits, known to form the classical fibronectin receptor, VLA-5, strongly. was more weakly variably; 3 occasional cells only. did not express 2, or other subunits tested.